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Gene Error Disrupts Touch-Based Learning

Research from The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology shows a gene called Syngap1 enables touch-based perception, while certain mutations can lead to mixed signals.
Immune cells and antibodies.
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How Trypanosomes Alter Their Antigen Expression To Evade the Immune System

Antigenic variation is a key mechanism by which pathogens evade the immune system. New research has shown how trypanosomes change their antigen expression.
Woman running on athletics track.
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Does More Exercise Really Lead to a Longer, Healthier Life?

Physical activity is seen as a way to extend the human lifespan, but Finnish twin studies found the benefits of physical activity for longevity may not be as straightforward as has been previously thought.
A bioprocessing scientist working on a large fermenter.
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Automation Accelerates Bioactive Natural Product Discovery

Natural products have become a mainstay in modern society and are used for numerous applications such as medicine and pesticides. Researchers have now developed a new method to accelerate bioactive natural product discovery.
The monkeypox virus against a black background.
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Tecovirimat Is Safe but Ineffective as a Treatment for Mpox

The antiviral drug tecovirimat used without other antivirals did not reduce the time to clinical resolution of clade II mpox lesions or improve pain control among adults in an international clinical trial sponsored by the NIH.
Neurons.
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Cold Temperatures Increase Neural Connections in Fly Brains

A study from Johannes Gutenberg University Mainz found that fruit flies raised at lower temperatures develop more neural connections in their olfactory system. Flies raised at 18°C had twice as many postsynaptic neurons as those at 25°C.
A woman holding her bump.
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Prenatal Stress Impacts Boys and Girls Differently

A study of 396 pregnant women found that prenatal stress timing affects infant stress reactivity and temperament differently by gender. Mid-gestation stress impacted girls, while late-gestation stress affected boys.
A pregnant woman's bump.
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Maternal Smoking Impacts Male Health More Than Female

A study of over 500,000 individuals links maternal smoking to genetic changes that impact offspring’s long-term health. Male children face higher risks, including early mortality and cancer, while women are more prone to reproductive issues.
Cancer cells.
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CRISPR Therapy Eliminates 50% of Head and Neck Tumors

Tel Aviv University researchers used CRISPR to cut the SOX2 gene from head and neck cancer cells, eliminating 50% of tumors in mice. The study highlights CRISPR’s potential for cancer treatment.
Bags of blood.
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How Regular Blood Donors Shape Their Stem Cell Genetics

Researchers found that frequent blood donation may favor genetic adaptations in blood stem cells, promoting healthy regeneration. While mutations in leukemia-associated genes were present, they differed from preleukemic variants.
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