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Latest App Notes & Case Studies

Image of a molecular structure surrounded by binary numbers and data imagery
App Note / Case Study

Advancing Quantitative Proteomics With Next-Gen DIA

This app note highlights a next-generation approach that enhances the depth of data-independent acquisition (DIA) while maintaining the precision of targeted workflows.
High-speed, high-parameter flow cytometry with advanced technology for precise cellular analysis.
App Note / Case Study

Unlock High-Speed, High-Parameter Flow Cytometry

Flow cytometers struggle with complex samples, slow rates, and panel limits. Next-gen technology enables fast, multidimensional analysis with acoustic-assisted hydrodynamic focusing and expanded spectral capabilities and data loss.
Cover for application note featuring guidelines on contamination management and laboratory balance maintenance
App Note / Case Study

How To Manage Contamination of Your Analytical Balance

This application note explores how a new generation of modern analytical balances benefit from hardware and software features that make cleaning processes easier and safer.
3D rendering of antibody-drug conjugates (ADCs) in a blue molecular environment, showcasing complex antibody structures.
App Note / Case Study

Streamlining the Analysis of Free Drug Content in ADCs

This application note presents a method that integrates protein elimination and free drug identification into one analysis using a two-dimensional liquid chromatography/quadrupole time-of-flight mass spectrometry (2D-LC/Q-TOF) approach.
Large spherical gas storage tanks at an industrial facility alongside molecular hydrogen representations against a blue sky
App Note / Case Study

Achieve Streamlined VOC Analysis in Ambient Air

This application note outlines a robust methodology for analyzing 65 VOCs in ambient air using canister sampling combined with thermal desorption-gas chromatography/mass spectrometry (TD-GC/MSD).
Cover page of a Bruker publication featuring a stylized visualization of protein structures.
App Note / Case Study

Simplifying Fusion Protein Characterization

This application note demonstrates how advanced LC-MS techniques provide comprehensive fusion protein characterization.
Cover page of a Bruker publication titled featuring a clean laboratory setting with bioprocessing equipment.
App Note / Case Study

Enhanced HCP Detection With Advanced Mass Spectrometry

This application note explores how the combination of advanced ion mobility technology, fragmentation processes and sensitive detection enable the identification of low-abundance peptides, metabolites and lipids in complex biological samples.
3D rendering of pink color Mitochondria against a plain light blue background
App Note / Case Study

Improve Insights Into Mitochondrial Function

This application note highlights how combining relative oxygen consumption rate (rOCR) assays with imaging technologies can transform mitochondrial research, featuring workflows and examples that simplify complex analyses.

Conjugal of DNA to primary antibodies with protein G and linker for multiplexed cellular targeting: 3D rendering
App Note / Case Study

Enhance Low-Abundance Proteomics Sensitivity

This app note explores how innovative scanning data-independent acquisition methods improve protein identification and quantitation at sub-nanogram levels.
A Cell Imaging screen showcasing an array of bright hues and intricate designs.
App Note / Case Study

Uncovering the Role of T Cells in Cancer With Spatial Biology

This application focus explores how high-plex spatial profiling can be applied to better understand the role of T cells in cancer immune surveillance and how cancers evade the immune system.
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