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A graphic illustration of a poison exon being removed from pre-mRNA. The exclusion of a posion exon allows for tumors to grow,
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Reactivating Cancer’s Molecular “Kill Switch”

In a recent study, scientists not only show how cancer hijacks this tightly regulated splicing and rearranging of RNA but also introduce a potential therapeutic strategy that could slow or even shrink aggressive and hard-to-treat tumors.
3D rendered microscopic image of T cells.
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Cancer Immunotherapy Enhanced by Rewiring T-Cell Metabolism

Researchers from the VIB-KU Leuven Center for Cancer Biology, in collaboration with other scientists, have discovered a way to enhance the immune system's ability to fight cancer by reprogramming T-cell metabolism.
3D rendered image of microscopic cancer cells.
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Metabolism Switch Fuels Pancreatic Cancer Spread

Researchers at the Garvan Institute of Medical Research have uncovered how pancreatic cancer hijacks a crucial metabolism ‘switch’ to help it spread, revealing a potential new treatment strategy for this highly aggressive disease.
MRI scans of the human brain.
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Repurposed Drug Shows Promise as a High-Grade Glioma Treatment

Avapritinib, an FDA-approved drug used to treat other types of cancer, also decreases aggressive gliomas in animal models and in an initial cohort of patients with high-grade glioma.
3D rendered image of cancer cells.
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Immunotherapy Resistant Proteins Identified in Colorectal Cancer

Researchers from Mayo Clinic have identified specific proteins — fibronectin and smooth muscle actin — within colorectal cancer tissues that are associated with resistance to immunotherapy treatment.
Blue Tit holding onto a branch.
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Why Do Some Species Resist Cancer Better Than Others?

A new study, led by researchers at Arizona State University, explores the relationship between diet, blood sugar (specifically glucose) and cancer prevalence across a broad range of vertebrate species.
Immunofluorescence images showing that cells with higher levels of the cancer-promoting MYC protein (red) also tend to exhibit high levels of DNA damage (green).
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Scientists Discover the Secret DNA Fueling Pancreatic Cancer

Pancreatic cancer has a notorious capacity to adapt and resist therapy. Now, a study uncovers a hidden driver of this adaptability: extrachromosomal DNA (ecDNA).
Cells with internal molecules visible.
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Metabolic Cause of Immune Cell Suppression Discovered

Researchers have uncovered critical mechanisms linked to metabolic insufficiencies that underlie plasmacytoid dendritic cell suppression after infection.
Orange sunset.
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Misconceptions About Skin Cancer Risk in the US

A new study explored associations between the reported number of sunburns and sociodemographic characteristics, in addition to examining the prevalence of protective skin behaviors adopted by the US adult population.
A pregnant woman's bump.
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Maternal Smoking Impacts Male Health More Than Female

A study of over 500,000 individuals links maternal smoking to genetic changes that impact offspring’s long-term health. Male children face higher risks, including early mortality and cancer, while women are more prone to reproductive issues.
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