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Reactivating Cancer’s Molecular “Kill Switch”
In a recent study, scientists not only show how cancer hijacks this tightly regulated splicing and rearranging of RNA but also introduce a potential therapeutic strategy that could slow or even shrink aggressive and hard-to-treat tumors.

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Cancer Immunotherapy Enhanced by Rewiring T-Cell Metabolism
Researchers from the VIB-KU Leuven Center for Cancer Biology, in collaboration with other scientists, have discovered a way to enhance the immune system's ability to fight cancer by reprogramming T-cell metabolism.

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Metabolism Switch Fuels Pancreatic Cancer Spread
Researchers at the Garvan Institute of Medical Research have uncovered how pancreatic cancer hijacks a crucial metabolism ‘switch’ to help it spread, revealing a potential new treatment strategy for this highly aggressive disease.

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Repurposed Drug Shows Promise as a High-Grade Glioma Treatment
Avapritinib, an FDA-approved drug used to treat other types of cancer, also decreases aggressive gliomas in animal models and in an initial cohort of patients with high-grade glioma.

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Immunotherapy Resistant Proteins Identified in Colorectal Cancer
Researchers from Mayo Clinic have identified specific proteins — fibronectin and smooth muscle actin — within colorectal cancer tissues that are associated with resistance to immunotherapy treatment.

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Why Do Some Species Resist Cancer Better Than Others?
A new study, led by researchers at Arizona State University, explores the relationship between diet, blood sugar (specifically glucose) and cancer prevalence across a broad range of vertebrate species.

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Scientists Discover the Secret DNA Fueling Pancreatic Cancer
Pancreatic cancer has a notorious capacity to adapt and resist therapy. Now, a study uncovers a hidden driver of this adaptability: extrachromosomal DNA (ecDNA).

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Metabolic Cause of Immune Cell Suppression Discovered
Researchers have uncovered critical mechanisms linked to metabolic insufficiencies that underlie plasmacytoid dendritic cell suppression after infection.

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Misconceptions About Skin Cancer Risk in the US
A new study explored associations between the reported number of sunburns and sociodemographic characteristics, in addition to examining the prevalence of protective skin behaviors adopted by the US adult population.

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Maternal Smoking Impacts Male Health More Than Female
A study of over 500,000 individuals links maternal smoking to genetic changes that impact offspring’s long-term health. Male children face higher risks, including early mortality and cancer, while women are more prone to reproductive issues.
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