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A model of a human heart.
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Researchers Uncover How the Heart Is Formed

Insights into the fundamental process of how the heart is formed offer new hope for treating heart disease. The findings focus on long, thin, channels of membranes – called Tunneling Nanotube-Like Structures - that connect cells together.
Glioblastoma stem cells with fluorescent labelling for prion protein (red), CD44 protein (green), and cell nucleus (blue).
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Blocking Prion Protein Slows Brain Cancer Progression

Researchers find that tumor stem cells became less able to proliferate and invade tissues when gene editing blocked the production of the prion protein; the results suggest that the molecule could be a therapeutic target.
3D rendered image of RNA
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RNA-Editing Protein May Improve Cancer and Autoimmune Disease Treatment

Researchers uncover new insights into the molecular mechanisms of ADAR1, a protein that regulates RNA-induced immune responses. Their findings could open new pathways for treating autoimmune diseases and enhancing cancer immunotherapy.
Zika Virus Particles Zika virus particles (red) shown in African green monkey kidney cells.
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Zika Builds Nanotubes to Cross Placenta

Researchers discovered that Zika virus constructs nanotubes to transport infection across the placental barrier undetected. The viral protein NS1 triggers this process, allowing Zika to spread while evading immune defenses.
Epithelial cells in the gut.
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Silent "Scream" of Epithelial Cells Detected for the First Time

Epithelial cells "talk" to each other with slow electrical signals, and "scream" to their neighbors when injured, new research has discovered.
Clusters of connective tissue cells, connected to one another.
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Winning Strategy in Mechanical Cell Competition Uncovered

New research challenges the classical interpretation of cell competition, revealing the importance of mechanical force.
A sketch of a human spinal column on a brown clipboard.
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Novel Cellular Mechanism May Inform Treatments for Congenital Spine Defects

Researchers have identified novel mechanisms regulating the development of the spinal column, which could inform new treatments for congenital scoliosis and other related birth defects.
A strand of RNA.
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RNA Origami Technique Produces Synthetic Cytoskeletons

Researchers have succeeded in producing nanotubes that fold into cytoskeleton-like structures, using a new RNA origami technique.
An illustration of the blood vessels in the brain.
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How Vascular Dysfunction Contributes to Neurodegenerative Disease

Researchers have revealed that vascular dysfunction can contribute to neurodegenerative diseases including Alzheimer's and ALS.
A graphic illustration of a poison exon being removed from pre-mRNA. The exclusion of a posion exon allows for tumors to grow,
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Reactivating Cancer’s Molecular “Kill Switch”

In a recent study, scientists not only show how cancer hijacks this tightly regulated splicing and rearranging of RNA but also introduce a potential therapeutic strategy that could slow or even shrink aggressive and hard-to-treat tumors.
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