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Bacteria in the gut.
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Early Antibiotic Use May Raise Diabetes Risk

A study from the University of Utah Health suggests early antibiotic use may disrupt insulin-producing beta cells, increasing the risk of metabolic disorders like type 1 diabetes.
The human gut comprised of bacteria.
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Bacterial Enzyme Could Aid Prebiotic and Therapeutic Research

A Tokyo University of Science study identifies a novel β-galactosidase in Bacteroides xylanisolvens that breaks down β-1,2-galactooligosaccharides. The enzyme could aid in prebiotic development and may inform treatments for diseases like Chagas.
Three antibodies against a black background.
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Antibody Combination May Help Combat Every SARS-CoV-2 Variant

A Stanford University-led team has found two antibodies that can work together to defeat all SARS-CoV-2 variants. More research is needed, but the approach could help in the development of treatments to keep pace with evolving viruses.
A tape measure used for measuring weight loss against a yellow background.
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AI Identifies Molecule That Rivals Ozempic for Weight Loss

A naturally occurring molecule resembles semaglutide in suppressing appetite and reducing body weight. Notably, animal testing also showed that it worked without some of the side effects of semaglutide.
Tau protein in the brain of a mouse with a mutation that causes a common form of dementia.
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Targeting Lysosomes Could Halt Tau Accumulation in Alzheimer’s

A study reveals how glutamate drives tau accumulation in Alzheimer’s and related disorders. Researchers found that blocking the gene KCTD20 activates lysosomes, helping clear toxic tau proteins in lab models.
Chromosome with orange lines wrapped around, illustrated gene editing.
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Can CRISPR Offer a Cure for Prader-Willi Syndrome?

Recent research from Duke University has demonstrated a promising new approach that could be used to treat a rare and complex class of genetic diseases, such as PWS, caused by defects in a relatively large region of the genome.
A close-up of a women's eyes.
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Stem Cell Therapy Repairs Blinding Corneal Damage in Trial

Mass Eye and Ear-led trial of procedure that took stem cells from a healthy eye and transplanted them into the damaged eye, safely restored corneal surfaces in 14 patients who were followed for 18 months.
COVID-19 virus particles.
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COVID-Flu Vaccine Provides Broad and Lasting Protection in Mice

Cornell researchers have developed a new vaccine platform that could provide more robust, longer-lasting protection from COVID-19 and influenza and broader immunity to different flu strains.
3D protein molecules showing the molecular backbone.
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Novel Reaction Enables the Precise Functionalization of Peptide Therapeutics

Researchers have applied a novel reaction to peptides produced using cell-free translation systems, providing a fast and efficient route to dehydrophenylalanine-containing structures.
A scientist holding a test tube in front of a model of DNA, representing gene therapy.
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Gene Therapy for Maple Syrup Urine Disease Shows Promise in Animal Study

A gene therapy to correct a mutation that causes maple syrup urine disease (MSUD) prevented newborn death, normalized growth, restored coordinated expression of the affected genes and stabilized biomarkers in a calf as well as in mice.
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