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Photograph of wildfire with glowing orange smoke.
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Extreme Weather Poses Risks for Cancer Patients

New research finds patients whose facility was impacted by a wildfire disaster during recovery from lung cancer surgery had longer length of stay (LOS) than similar patients treated at the same facility, but when no disaster occurred.
Cancer cells.
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CRISPR Therapy Eliminates 50% of Head and Neck Tumors

Tel Aviv University researchers used CRISPR to cut the SOX2 gene from head and neck cancer cells, eliminating 50% of tumors in mice. The study highlights CRISPR’s potential for cancer treatment.
Bags of blood.
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How Regular Blood Donors Shape Their Stem Cell Genetics

Researchers found that frequent blood donation may favor genetic adaptations in blood stem cells, promoting healthy regeneration. While mutations in leukemia-associated genes were present, they differed from preleukemic variants.
Purple cancer cells invade into normal lung cells.
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Noncancerous Cells Exert Powerful Influence Over Tumor Cells

Researchers have developed a "colocatome" that illustrates how noncancerous cells affect their neighboring tumor cells.
A group of cancer cells shown in red, the target of the newly developed CAR T-cell therapy.
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Next-Generation CAR T-Cell Therapy Designed for Hard-To-Treat Cancers

Researchers at the University of Colorado Anschutz Medical Campus have successfully developed an iteration of CAR-T cell therapy that can enhance the effectiveness and longevity of the cells, particularly against hard-to-treat cancer cells.
Strands of DNA.
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Hidden Mechanics of DNA Replication Reveal Cancer Drug Target

Researchers have uncovered a source of "replication stress" during DNA replication, shedding light on a new cancer target.
Immune cells attacking cancer cell.
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Cerebrospinal Fluid Proteins Could Predict Cancer Immunotherapy Side Effect

Certain proteins in cerebrospinal fluid could act as key indicators for a harmful side effect of cancer immunotherapy, offering hope for early treatment or even prevention of this neurotoxic condition.
Firefighters battling to control flames.
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Mutational Signature in Gliomas Tied to Chemical Exposure in Firefighters

Using glioma tumor samples, researchers looked for genetic mutational signatures, finding one previously associated with exposure to haloalkene, a substance found in flame retardants, fire extinguishers, and pesticides.
Weighing scales.
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Chronic Stress and Obesity Fuel Pancreatic Cancer Development

A new study led by UCLA investigators suggests that chronic stress and an unhealthy diet may work together to fuel the early development of pancreatic cancer, shedding light on how lifestyle factors contribute to one of the deadliest malignancies.
Doctor filling out questionnaire.
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Increasing Cancer-Gene Testing Efforts in Primary Care

A new study assessed two ways that primary-care practices could assess patients’ hereditary cancer risks and deliver testing to those identified as higher risk.
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