Latest Whitepapers

As researchers endeavor to map the architecture of the brain, many rely on tissue dissociation approaches to prepare single-cell suspensions for downstream analysis. Howev er, such conventional methods can involve enzymes and heat, which are known to induce transcriptional and proteotype changes in brain cells.

Cell culture is essential for a variety of applications including disease modeling, drug discovery, cell-based manufacturing and genetic engineering.

The rapid and accurate identification of microbial contaminants is crucial for quality control in pharmaceutical processes and products. However, until recently, testing labs have relied on time-consuming phenotypic approaches.

This whitepaper highlights specific case studies that reveal how researchers are applying nanopore technology to a variety of sequencing techniques, including whole genome, targeted, RNA sequencing and single-cell analysis.

This whitepaper highlights the recent developments and performance of three modular benchtop solutions for the high-performance quantitation and kinetics characterization of proteins and their small molecule interactions.

This whitepaper highlights the features and capabilities of a novel system for streamlining affinity analysis for rapid lead molecule screening.

Flow cytometry is an important part of the drug discovery workflow. From screening antibodies to small molecules, combining tests for various analytes in a single panel not only reduces the necessary sample volume but also collects more information in less time, accelerating the drug discovery process.

Rather than choosing between the detail of single-cell RNA sequencing and the in situ capabilities of conventional immunohistochemistry, spatial phenotyping allow you to visualize and quantify dozens of biomarkers in a single tissue sample while maintaining cellular and sub-cellular detail.

Recent technological advancements have made single-cell sequencing an increasingly powerful tool for understanding biology and cellular function, disease diagnosis, therapy response prediction, and treatment selection.

In 2012, the Harvard Brain Tissue Resource Center lost 150 of its stored frozen brain samples, including one third of the world’s largest collection of autism brain tissue.