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A man with depression sitting in bed.
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GLP-1 Drugs May Offer Antidepressant Effects

GLP-1RAs, a class of glucose-lowering medication used to treat diabetes and obesity, may offer antidepressant effects. UF researchers studied Medicare claims data of older adults with Type 2 diabetes to assess their risk of depression.
A close up of the leaves of a cannabis plant.
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Cannabis Terpenes Relieve Fibromyalgia Pain in Preclinical Models

Terpenes from the Cannabis sativa plant may be a viable medication for fibromyalgia and post-surgical pain relief, according to University of Arizona Health Sciences research published in Pharmacological Reports.
The monkeypox virus against a black background.
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Tecovirimat Is Safe but Ineffective as a Treatment for Mpox

The antiviral drug tecovirimat used without other antivirals did not reduce the time to clinical resolution of clade II mpox lesions or improve pain control among adults in an international clinical trial sponsored by the NIH.
A man dipping a finger into a pot of skincare cream containing a natural ingredient that could help treat skin lupus.
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A Natural Ingredient Found in Skincare Could Help Treat Lupus

A new study co-led by the University of Zurich has now shown that the natural active ingredient gluconolactone restores immune regulation, reduces inflammation and could enable targeted therapy with fewer side effects.
White drugs against a blue background.
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Gold Nanoparticles Reveal Drug Distribution in Mice

A recent study by Tokyo’s Waseda University, reports a novel imaging technique that allows direct and highly sensitive tracking of drugs inside the body using gold nanoparticles.
A scientist holding a red drug, which could have been designed using fragment-based drug discovery.
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Fragment-Based Drug Discovery Platform Identifies Possible Sepsis Treatments

Researchers have created a fragment-based drug discovery platform and tested tiny fragments of future drugs that may lead to new therapies to treat sepsis.
A cell with organelles visible, including the Golgi apparatus.
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Controlling Cell Acidity Could Be Key to Autoimmune Disease Treatment

What if treating autoimmune diseases was as simple as regulating the acidity levels of parts of patients’ cells? New research indicates that controlling cell acidity could treat severe inflammation.
A mosquito hangs upside down from a leaf.
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Mosquito Protein Quality Control System Offers New Antimalarial Target

The molecular quality control system, called the prefoldin chaperonin system, in Anopheles mosquitoes could be a promising target for malaria control strategies.
Various types of weight loss drug on top of a tape measure used for measuring weight loss.
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Expanding Stomach Capsule Produces Sustained Weight Loss

A new weight loss treatment, Sirona, expands in the stomach to curb hunger. Phase 2 trials show promising results and the treatment could help transition patients off GLP-1 medications.
A female doctor showing clinical trial results to a Black female patient.
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Diversifying Clinical Trial Investigators Could Help Diversify Enrollment

New findings suggest that diversifying the leadership of clinical trials could improve enrollment by underrepresented groups including Black Americans, who comprise 13% of the U.S. population but just 5% of clinical trial participants.
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