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GLP-1 Drugs May Offer Antidepressant Effects
GLP-1RAs, a class of glucose-lowering medication used to treat diabetes and obesity, may offer antidepressant effects. UF researchers studied Medicare claims data of older adults with Type 2 diabetes to assess their risk of depression.

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Cannabis Terpenes Relieve Fibromyalgia Pain in Preclinical Models
Terpenes from the Cannabis sativa plant may be a viable medication for fibromyalgia and post-surgical pain relief, according to University of Arizona Health Sciences research published in Pharmacological Reports.

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Tecovirimat Is Safe but Ineffective as a Treatment for Mpox
The antiviral drug tecovirimat used without other antivirals did not reduce the time to clinical resolution of clade II mpox lesions or improve pain control among adults in an international clinical trial sponsored by the NIH.

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A Natural Ingredient Found in Skincare Could Help Treat Lupus
A new study co-led by the University of Zurich has now shown that the natural active ingredient gluconolactone restores immune regulation, reduces inflammation and could enable targeted therapy with fewer side effects.

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Gold Nanoparticles Reveal Drug Distribution in Mice
A recent study by Tokyo’s Waseda University, reports a novel imaging technique that allows direct and highly sensitive tracking of drugs inside the body using gold nanoparticles.

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Fragment-Based Drug Discovery Platform Identifies Possible Sepsis Treatments
Researchers have created a fragment-based drug discovery platform and tested tiny fragments of future drugs that may lead to new therapies to treat sepsis.

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Controlling Cell Acidity Could Be Key to Autoimmune Disease Treatment
What if treating autoimmune diseases was as simple as regulating the acidity levels of parts of patients’ cells? New research indicates that controlling cell acidity could treat severe inflammation.

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Mosquito Protein Quality Control System Offers New Antimalarial Target
The molecular quality control system, called the prefoldin chaperonin system, in Anopheles mosquitoes could be a promising target for malaria control strategies.

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Expanding Stomach Capsule Produces Sustained Weight Loss
A new weight loss treatment, Sirona, expands in the stomach to curb hunger. Phase 2 trials show promising results and the treatment could help transition patients off GLP-1 medications.

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Diversifying Clinical Trial Investigators Could Help Diversify Enrollment
New findings suggest that diversifying the leadership of clinical trials could improve enrollment by underrepresented groups including Black Americans, who comprise 13% of the U.S. population but just 5% of clinical trial participants.
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