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Next-Generation CAR T-Cell Therapy Designed for Hard-To-Treat Cancers
Researchers at the University of Colorado Anschutz Medical Campus have successfully developed an iteration of CAR-T cell therapy that can enhance the effectiveness and longevity of the cells, particularly against hard-to-treat cancer cells.

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Temperature May Control Protein Shapeshifting
Scientists propose that temperature is a key trigger for metamorphic proteins, enabling them to switch between shapes. Their study suggests temperature-dependent hydrophobic interactions drive this transformation.

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Common Herbs Inspire a Potential Anti-Inflammatory Alzheimer’s Drug
Scripps Research scientists have created a stable form of carnosic acid, a compound found in rosemary and sage, observing greater memory function and other disease improvements in mice.

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Estrogen May Protect Against Opioid Misuse in Chronic Pain
A study finds that male rats in chronic pain escalate fentanyl use, while females maintain stable doses due to estrogen’s effects. Pain amplified dopamine release in males, driving increased opioid-seeking behavior.

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Repurposed ALS Drug Helps Diagnose Neurodegeneration
Scientists at St. Jude Children’s Research Hospital have used positron emission tomography (PET) with edaravone, a drug used to treat ALS, to detect oxidative stress, which leads to brain damage.

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Consuming THC While Pregnant May Impact Fetal Lung Development
Oregon Health & Science University researchers have found that consuming cannabis while pregnant could affect fetal lung development and function, potentially leading to the development of chronic respiratory health conditions.

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Novel Method To Regenerate Heart Muscle Offers Hope for Heart Failure Treatment
A discovery in cardiac regeneration offers ew hope for the treatment of ischemic heart failure. Published in npj Regenerative Medicine, the study reveals a novel approach to promoting cardiomyocyte proliferation.

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Strains of Aspergillus fumigatus Five Times More Likely To Acquire Resistance to Antifungals
Researchers have identified strains of one of the world's most dangerous pathogens that are five times more likely to acquire antifungal resistance.

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Heat-Activated Receptor Could Unlock New Pain Therapies
Researchers have uncovered a heat-based activation mechanism for a critical pain receptor, opening new avenues for therapeutic targets that treat pain.

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Melatonin Protects Muscle From Damage Caused by Obesity and Diabetes
Researchers show that melatonin improves muscle energy efficiency and could become an innovative therapy to combat obesity and type 2 diabetes.
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