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3D rendered image of blue DNA helix.
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Discovering the Genetic Drivers of Aggressive Prostate Cancer

Scientists from UCLA, the University of Toronto and the University of Melbourne have uncovered new genetic clues that explain why some prostate cancers remain slow-growing while others become life-threatening.
The Pol-theta enzyme (blue) joins two parts of a broken DNA strand (yellow). This process is mutagenic and can give rise to cancer.
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Mechanism of Key DNA Repair Protein Advances Cancer Treatment

Scientists at Scripps Research have now captured the first detailed images of the DNA repair protein, Pol-theta, in action, revealing the molecular processes responsible for a range of cancers.
Tattoo artist tattooing an individual.
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Tattoo Ink May Increase Skin and Lymphoma Cancer Risk

Researchers have found indications that tattoo ink may increase the risk of skin and lymphoma cancers, due to the tattoo ink accumulating in the lymph nodes. The findings raise new questions about the long-term health effects of tattoos.
Representation of a neuroblastoma cancer cell.
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How Retinoic Acid Works To Treat Neuroblastoma

Scientists at St. Jude Children’s Research Hospital have uncovered the mechanism by which retinoic acid selectively kills metastatic neuroblastoma cells, with little effect on primary tumors.
3D rendered microscopic image of cancel cells.
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New Treatment Strategy Increases Cell Death in Leukemia

Scientists at VCU Massey Comprehensive Cancer Center have identified an innovative combination of treatment strategies that work collaboratively to effectively kill acute myeloid leukemia (AML) cells, a frequently incurable form of cancer.
3D rendered DNA helix
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Co-Occurring Mutations Drive Therapy Resistance in KRAS G12C Cancers

Colorectal cancer and pancreatic ductal adenocarcinoma that harbored the KRAS G12C mutation often carried other genetic alterations that can be associated with resistance to KRAS G12C inhibitors.
An immune cell.
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How Do Brain Cancer Cells Reprogram Immune Cells?

New research has uncovered a mechanism by which brain cancer cells reprogram immune cells from fighting cancer to enabling tumor growth.
Scientist loading PCR plate.
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“Ultra-Rapid” Testing Determines Cancerous Cells in the Operating Room

A novel tool for rapidly identifying the genetic “fingerprints” of cancer cells may enable future surgeons to more accurately remove brain tumors while a patient is in the operating room, new research reveals.
A cluster of cancer cells.
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Reprogramming Aggressive Cancer Cells Into Harmless Ones

UCLA scientists have identified a potential new strategy for treating glioblastoma, the deadliest form of brain cancer, by reprogramming aggressive cancer cells into harmless ones.
A group of cancer cells requiring cancer immunotherapy that often uses anti-swelling drugs.
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Commonly Prescribed Anti-Swelling Drug Suppresses Immune Response

While controlling swelling caused by brain cancer is important, a new study shows that a commonly prescribed anti-swelling drug suppresses the immune system for weeks after dosage, inhibiting the body’s ability to fight the cancer.
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