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Here we describe a live cell imaging based approach to detect GPCR activation using the Lionheart™ FX Automated Live Cell Imager and Gen5™ Microplate Reader and Imager Software.

In this study, the role of miRNAs has been assessed in a large cohort of pancreatic cancer.

Our objective is to validate diagnostic services using Oxford Nanopore’s Minion in the first instance and to evaluate the cost and performance compared to existing sequencing technology in areas such as tumour DNA sequencing (and circulating tumour DNA), virology, microbiology, genetics and HLA-typing.

Here we report the creation and characterization of a unique inhibitor of CK2a that targets a novel cryptic pocket and was developed using fragment-based methods.

MRI has several advantages relative to other imaging modalities in evaluating, diagnosing, and planning treatment for prostate cancer. However, it is rarely ordered for localized disease. While the diagnostic abilities have been studied, little has been done to associate clinical outcomes with prostate cancer patients who received MRI.

This study hypothesis is that the secondary cancers that develop in patients with KS have changed.

This data indicates that AA exhibits anti-cancer effects in vitro through an OxS mechanism and that HBOT can enhance this therapeutic effect.

These preliminary results show antitumor activity of adoptive cell transfer of MHC class mismatched CD4(+) T-cells. The finding of reduced numbers of pulmonary metastases correlates with increased serum anti-OVA IgG and increased germinal center development in the spleen.

We have discovered novel small molecule compounds that directly induce PTEN function and antagonize PI3K/AKT pathway activity in lung cancer cells.

We review perioperative and oncological outcomes and compare survival between ILI and amputation.