Latest App Notes & Case Studies

Chinese hamster ovary (CHO) is the cell line of choice in many biotherapeutic production workflows. Yet, in the early stages of drug development, CHO lines require high-performing, chemically defined media optimized for their specific needs.

When planning for your sample storage needs, there’s no doubt you’ve discovered the many types of freezers on the market—upright, under-counter, side-by-side, and chest, to name a few. So, what advantages do chest freezers have over other types of freezers?

In this app note, learn more about the advantages of batch centrifugation and how you can optimize downstream processing of primary T cells, and share some exemplary results for viability and recovery of T cells after washing and concentration.

The composition of the cryopreservation medium can have a big impact on the recovery of viable cells after thawing. Learn how long-term cryopreservation with MACS® Freezing Solution can maintain the viability and stability of cell suspensions and tissue samples.

Pluripotent stem cells are the gateway to creating cells for disease modeling, regeneration and drug discovery. When it comes to growing such infinite potential, selecting the right culture medium is key!

This application note outlines the importance of reagent consistency in organoid tissue culture.

Many targets implicated in diseases are refractory to knockdown by traditional therapeutics like antibodies and small molecules. They represent an exciting new modality, repurposing small molecule chemical tools to achieve selective degradation

The ability to study transcript isoforms in detail could have a significant impact on our understanding of health and disease. However, most commonly, bulk sequencing is the selected method that only provides an average of the transcripts expressed across your sample of cells.

Protein-targeting chimeras (PROTACs) have gained significant attention recently due to their high potency in nanomolar drug concentrations and target selectivity. However, low test concentrations in complex matrices present analytical challenges.

Download this app note to learn how you can select 20 individual CTCs in 10 minutes, this approach can be used for DNA, RNA or proteome analysis as well as how these target cells are selected and isolated in high purity from heterogenous backgrounds.