News

Successful high-affinity B cells can proliferate under special conditions that reduce the risk of mutation. Capturing this mechanism in the lab may lead to more efficient vaccine strategies in the clinic.

A protein called angiopoietin-2 (ANGPT2) can both inhibit and encourage blood vessel changes critical for sepsis, a leading cause of hospital deaths worldwide.

Scientists have identified a key component to launching immune activity – and overactivity. The researchers identified a protein in cells that spurs the release of infection-fighting molecules.

Researchers found gut bacteria in brain implants, potentially causing inflammation and reducing device function. The study suggests that medical implants may breach the blood-brain barrier, allowing microbes to enter.

Scientists at St. Jude Children’s Research Hospital have found that frequently used antivirals do not work well against the H5N1 avian influenza virus in cows’ milk.

Researchers uncover new insights into the molecular mechanisms of ADAR1, a protein that regulates RNA-induced immune responses. Their findings could open new pathways for treating autoimmune diseases and enhancing cancer immunotherapy.

Researchers discovered that Zika virus constructs nanotubes to transport infection across the placental barrier undetected. The viral protein NS1 triggers this process, allowing Zika to spread while evading immune defenses.

A National Institutes of Health (NIH)-sponsored clinical trial of a candidate vaccine to prevent Lassa fever has begun enrolling participants at the University of Maryland School of Medicine, Baltimore.

New research illustrates how a DNA repair protein suppresses senescent cells, reducing age-associated chronic inflammation.

Mount Sinai researchers have developed a method to uncover the hidden immune cells that harbor the human immunodeficiency virus.