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Optimized Flow Cytometry for Natural Killer Cell Analysis

Attune Xenith flow cytometry optical deck enabling precise, high-speed cell analysis with advanced detection technology.
Credit: Thermo Fisher Scientific

Natural killer (NK) cells play a vital role in immune defense, targeting infected and cancerous cells through specific marker recognition. Understanding NK cell activation, inhibition and maturation requires advanced analytical tools to ensure accurate characterization. Yet, traditional flow cytometry methods often struggle with marker overlap and limited detection sensitivity, creating challenges in complex immunophenotyping.


This application note explores an innovative spectral flow cytometry method optimized for NK cell characterization. 


Download this application note to explore:
  • A 25-marker spectral panel optimized for NK cell activation and maturation analysis 
  • Advanced spectral unmixing techniques to improve marker resolution
  • How high-throughput flow cytometry enables efficient and precise NK cell characterization



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